As stress may incur an excess of glucocorticoids or reductions in neurotrophin levels which are thought to be associated with decreased astrocytic density and impaired astrocytic function, it may, in turn, lead to disruption of glutamatergic system and subsequent neurotoxicity The insults: Infection, chronic stress, trauma, drugs, etc
Chronic conditions like Long COVID and ME/CFS can deplete glutathione, driving severe fatigue and brain fog
This is because sulfur molecules comprise the more complex glutathione compound, so without sulfur, theres less glutathione present in the body
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